Seven years after the tragic death of her brother Donnie, Samantha Darko is still mourning him and the loss of the loving family that fell apart after he died. Her home life in shambles, 18-year-old Sam impulsively decides to join her rebellious best friend Corey on a cross-country drive from Virginia to California in the hope of becoming a professional dancer. Sam and Corey have a bitter falling out that ends in catastrophe. Without realizing it, they become links in an invisible chain that connects them to a missing child, a disturbed Gulf war veteran and a dangerous hole in time and space. Only a sacrifice of the highest order will return the universe to its proper time and place, and the clock is ticking.