Jai (Govinda) and Veeru (Sanjay Dutt) are partners and friends in crime. That is why their friendship is called Jodi No. 1. They dupe people after gaining their confidence. But they have to run from Bombay after a clash with a local Bhai. In the course of their travel, they happen to meet Inder (Rajat Bendi), an NRI, who is on his way to Goa to work as a manager for Rai Bahdur (Anupam Kher), a wealthy businessman, who owns a beer factory.