Simona Brhlikova was born in Czechoslovakia. In early childhood and at a young age starred in several stage and musical productions.
Graduating from Commerce & Language Academy in Slovakia, Simona moved to London where she perfected her English with Cambridge First Certificate at University College London, and trained at RADA and The Actors Center. She also speaks 7 languages.
Simona's first worked in theatre in London, in productions like Much Ado About Nothing, As You Like It, Queen of Spades. This then led to a string of independent films, including a major role in Lycanthropy (2006), alongside George Calil and David Bradley, and then to television work on such shows as The IT Crowd, Life Begins, Footballers' Wives, Bad Girls and Casanova's Love Letters.
Moving onto international projects, Brhlikova landed the role of the villainess "Kisscut" in Gallowwalker starring opposite Wesley Snipes, and Maddoff: Made off with America about the infamous Ponzi schemer Bernie, playing mastermind "Ursula aka Mrs X".
Simona now lives and works in Hollywood, USA.