Misa Shimizu is a Japanese actress. She made her screen debut by winning the heroine audition for 1987 film Sh?nan B?s?zoku. She starred in NHK's morning drama series Seishun Kazoku in 1989. She portrayed Keiko, the female protagonist, in Palme d'Or winning The Eel directed by Shohei Imamura. She also makes regular appearances in Masayuki Suo's films. She won the award for best actress at the 17th Hochi Film Award for Okoge, Sumo Do, Sumo Don't, Future Memories: Last Christmas.