Antonella Ponziani is an Italian actress.
Born in Rome, she attended the academy Mimo Teatro Movimento, under the guidance of Lidia Biondi. She debuted in 1986, in Salvatore Samperi's Le bonne.
In 1992 Antonella Ponziani won a Silver Ribbon for Best Actress and a David di Donatello in the same category for the film Verso Sud.
In 1996 she won a Ciak d'oro for Best Supporting Actress for her performance in Ferie d'Agosto by Paolo Virzì.
In 1999 she debuted as director with the comedy film L'ultimo Mundial, in which she also appeared as an actress and screenwriter.